Biologia plantarum 7:86-92, 1965 | DOI: 10.1007/BF02920623
Adaptability in enzymes
- 1 Chemistry Department, University of Allahabad, Allahabad, India
In studying inhibitors and activators of enzymes it has often been found that inhibitors act as activators when in very low concentrations and that certain activators (in suitable concentrations) show inhibition. Similar results were obtained in the present work in studying urease from soya bean in the presence of lead acetate. Lead acetate is normally an inhibitor of urease. It was found, however, that in small concentrations of lead acetate increase in the activity of urease occurs. On prolonging the time of the reaction inhibition develops and still later increased enzymatic activity again occurs. The results were elaborated statistically and are discussed in relation to the use of "adaptation" of urease in unfavourable conditions in reaction mixtures by the action of lead acetate.
Received: August 20, 1964; Published: March 1, 1965 Show citation
References
- Bahadur, K., Chandra, V.: Inhibition of urease by lead-acetate. Enzymologia XX: 355-358, 1959.
- Bahadur, K., Chandra, V.: Influence of enzyme and substrate concentration on the decomposition of urea by commercial urease and urease obtained from glycine soyabeans in phosphate buffer. Enzymologia XXIII: 117-122, 1961.
- Bahadur, K., Atreya, B. D.: Influence of aminoacids and amines on the enzymic activity of papain. Proc. Natl. Acad. Sci. (India)30: 126-140, 1961.