biologia plantarum

International journal on Plant Life established by Bohumil Němec in 1959

Biologia plantarum 48:161-166, 2004 | DOI: 10.1023/B:BIOP.0000033439.34635.a6

Ascorbic Acid Oxidase: An Enzyme in Search of a Role

M.C. De Tullio1, R. Liso1, O. Arrigoni1,*
1 Dipartimento di Biologia e Patologia Vegetale, Università di Bari, Bari, Italia

Ascorbic acid oxidase (AAO) has been fully characterized at molecular level, yet its functional role is unclear. The properties of the enzyme and the main hypotheses on its function are discussed. Recent data and reappraisal of previous observations suggest that AAO could be part of a dynamic mechanism operating whenever plant cells have to control oxygen availability.

Keywords: ascorbic acid; dioxygen
Subjects: ascorbate, ascorbic acid; ascorbic acid oxidase; auxins; dehydroascorbic acid, dehydroascorbate reductase; dendrogram, phylogenetic tree; glutathione reductase; phylogenetic tree, dendrogram; polymerase chain reaction (PCR)

Published: June 1, 2004  Show citation

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De Tullio, M.C., Liso, R., & Arrigoni, O. (2004). Ascorbic Acid Oxidase: An Enzyme in Search of a Role. Biologia plantarum48(2), 161-166. doi: 10.1023/B:BIOP.0000033439.34635.a6
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References

  1. Arrigoni, O., Chinni, E., Ciraci, S., De Tullio, M.C.: In vivo elicitation of ascorbate oxidase activity by dioxygen and its possible role in photosynthesizing leaves.-Rend. Fis. Acc. Lincei 14: 127-134, 2003. Go to original source...
  2. Arrigoni, O., De Tullio, M.C.: Ascorbic acid: much more than just an antioxidant.-Biochim. biophys. Acta 1569: 1-9, 2002. Go to original source...
  3. Chichiriccò, G., Cerù, M.P., D'Alessandro, A., Oratore, A., Avigliano, L.: Immunohistochemical localisation of ascorbate oxidase in Cucurbita pepo medullosa.-Plant Sci. 64: 61-66, 1989. Go to original source...
  4. Diallinas, G., Pateraki, I., Sanmartin, M., Scossa, A., Stilianou, E., Panopoulos, N.J., Kanellis, A.K.: Melon ascorbate oxidase: cloning of a multigene family, induction during fruit development and repression by wounding.-Plant mol. Biol. 34: 759-770, 1997. Go to original source...
  5. Esaka, M.: Gene expression and function of ascorbate oxidase in higher plants.-Recent Res. Dev. Phytochem. 2: 315-326, 1998.
  6. Esaka, M., Fujisawa, K., Goto, M., Kisu, Y.: Regulation of ascorbate oxidase expression in pumpkin by auxin and copper.-Plant Physiol. 100: 231-237, 1992. Go to original source...
  7. Farver, O., Pecht, I.: Low activation barriers characterize intramolecular electron transfer in ascorbate oxidase.-Proc. nat. Acad. Sci. USA 89: 8283-8287, 1991.
  8. Farver, O., Wherland, S., Pecht, I.: Intramolecular electron transfer in ascorbate oxidase is enhanced in the presence of oxygen.-J. biol. Chem. 269: 22933-22936, 1994. Go to original source...
  9. Fleming, R.E., Whitman, I.P., Gitlin, J.D.: Induction of ceruloplasmin gene expression in rat lung during inflammation and hyperoxia.-Amer. J. Physiol. 260: L68-L74, 1991. Go to original source...
  10. Floris, G., Medda, R., Padiglia, A., Musci, G.: The physiopathological significance of ceruloplasmin.-Biochem. Pharmacol. 60: 1735-1741, 2000. Go to original source...
  11. Hidalgo, A., Garcia-Herdugo, G., Gonzalez-Reyes, J.A., Morrè, D.J., Navas, P.: Ascorbate free radical stimulates onion root growth by increasing cell elongation.-Bot. Gaz. 152: 282-288, 1991. Go to original source...
  12. Horemans, N., Asard, H., Caubergs, R.J.: Carrier mediated uptake of dehydroascorbate into higher plant plasma membrane vescicles shows trans-stimulation.-FEBS Lett. 421: 41-44, 1998. Go to original source...
  13. James, W.O., Boulter, P.: Further studies of the terminal oxidases in the embryos and young roots of barley.-New Phytol. 54: 1-12, 1955. Go to original source...
  14. Kato, N., Esaka, M.: Changes in ascorbate oxidase gene expression and ascorbate levels in cell division and cell elongation in tobacco cells.-Physiol. Plant. 105: 321-329, 1999. Go to original source...
  15. Kato, N., Esaka, M.: Expansion of transgenic tobacco protoplasts expressing pumpkin ascorbate oxidase is more rapid than that of wild-type protoplasts.-Planta 210: 1018-1022, 2000. Go to original source...
  16. Kerk, N.M., Feldman, L.J.: A biochemical model for the initiation and maintenance of the quiescent center: implications for organization of root meristems.-Development 121: 2825-2833, 1995. Go to original source...
  17. Kerk, N.M., Jiang, K., Feldman, L.J.: Auxin metabolism in the root apical meristem.-Plant Physiol. 122: 925-932, 2000. Go to original source...
  18. Kroneck, P.M.H., Armstrong, F.A., Merkle, H., Marchesini, A.: Ascorbate oxidase: molecular properties and catalytic activity.-In: Seib, P.A., Tolbert, B.M. (ed.): Advances in Chemistry; Ascorbic Acid: Chemistry, Metabolism and Uses. Pp. 223-247. American Chemical Society, Washington 1982. Go to original source...
  19. Lin, L.S., Varner, J.E.: Expression of ascorbic acid oxidase in zucchini squash (Cucurbita pepo L.).-Plant Physiol. 96: 159-165, 1991. Go to original source...
  20. Liso, R., Calabrese, G., Bitonti, M.B., Arrigoni, O.: Relationship between ascorbic acid and cell division.-Exp. cell. Res. 150: 314-320, 1984. Go to original source...
  21. Liso, R., Innocenti, A.M., Bitonti, M.B., Arrigoni, O.: Ascorbic acid-induced progression of quiescent centre cells from G1 to S phase.-New Phytol. 110: 469-471, 1988. Go to original source...
  22. Marchesini, A., Capelletti, P., Canonica, L., Danieli, B., Tollari, S.: Evidence about the catecholoxidase activity of the enzyme ascorbate oxidase extracted from Cucurbita pepo medullosa.-Biochim. biophys. Acta 484: 290-300, 1977. Go to original source...
  23. Mertz, D.: Distribution and cellular localization of ascorbic acid oxidase in the maize root tip.-Amer. J. Bot. 48: 405-413, 1961. Go to original source...
  24. Messerschmidt, A., Huber, R.: The blue oxidases, ascorbate oxidase, laccase and ceruloplasmin.-Eur. J. Biochem. 187: 341-352, 1990.
  25. Messerschmidt, A., Rossi, A., Ladenstein, R., Huber, R., Bolognesi, M., Gatti, G., Marchesini, A., Petruzzelli, R., Finazzi-Agrò, A.: X-ray crystal structure of the blue oxidase ascorbate oxidase from zucchini.-J. mol. Biol. 206, 513-529, 1989. Go to original source...
  26. Ohkawa, J., Okada, N., Shinmyo, A., Takano, M.: Primary structure of cucumber (Cucumis sativus) ascorbate oxidase deduced from cDNA sequence: Homology with blue copper proteins and tissue-specific expression.-Proc. nat. Acad. Sci. USA 86: 1239-1243, 1989. Go to original source...
  27. Pignocchi, C., Fletcher, J.M., Wilkinson, J.E., Barnes, J.D., Foyer, C.H.: The function of ascorbate oxidase in tobacco.-Plant Physiol. 132: 1631-1641, 2003. Go to original source...
  28. Potters, G., De Gara, L., Asard, H., Horemans, N.: Ascorbate and glutathione: guardians of the cell cycle, partners in crime?-Plant Physiol. Biochem. 40: 537-548, 2002. Go to original source...
  29. Raven, J.A., Johnston, A.M., Parsons, R., Kübler, J.: The influence of natural and experimental high O2 concentrations on O2-evolving phototrophs.-Biol. Rev. 69: 61-94, 1994. Go to original source...
  30. Reddy, K.P., Khan, P.A., Patnaik, S., Mohanty, G.B., Kumar, K.B.: Ascorbate oxidase activity in rice shoot apices during panicle initiation.-Plant Cell Physiol. 27: 725-728, 1986.
  31. Sanmartin, M., Drogoudi, P.D., Lyons, T., Pateraki, I., Barnes, J., Kanellis, A.K.: Over-expression of ascorbate oxidase in the apoplast of transgenic tobacco results in altered ascorbate and glutathione redox states and increased sensitivity to ozone.-Planta 216: 918-928, 2003. Go to original source...
  32. Szent-Györgyi, A.: On the function of hexuronic acid in the respiration of the cabbage leaf.-J. biol. Chem. 90: 385-393, 1931. Go to original source...
  33. Tommasi, F., De Gara, L., Liso, R., Arrigoni, O.: The ascorbic acid system in Cuscuta reflexa Roxb.-J. Plant Physiol. 135: 766-768, 1990. Go to original source...